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Langendorff Isolated Perfused
Heart
Informative and Economical
- High sensitivity and
specificity
- Explores electrophysiological
and mechanical parameters
- Quantifies coronary
vascular resistance
- Millisecond accuracy
for measuring QT and QT
Instability.
- Identifies the NOAEL
- GLP Compliant
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Lead optimization: Studies conducted
at QTest Labs permit identifying
“lead” compounds
that possess lowest potential
for developing cardiovascular
toxicity.
Comprehensive assessment of
all important cardiovascular
parameters: Test articles may
produce toxicity on any or all
properties of cardiovascular
function (e.g., chronotropy,
dromotropy, irritability, inotropy,
lusitropy, vascular resistance,
baroreceptor sensitivity). QTest
Labs interrogates the effects
of test articles on all these
properties.
Studies are performed in compliance
with GLP regulations, and are
compatible with ICH guidelines
for safety pharmacology. |
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